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RECENT ADVANCES IN PHARMACEUTICAL RHEOLOGY
1Dept. of Pharmacy, Portsmouth Polytechnic, Portsmouth, England.
Journal of Texture Studies
|April 4, 2017
Summary
This review covers pharmaceutical rheology advancements since 1965, focusing on powders, suspensions, semi-solids, emulsions, suppositories, and aerosols. It synthesizes 292 references to detail material properties and behaviors.
Area of Science:
- Pharmaceutical Sciences
- Materials Science
- Physical Chemistry
Background:
- The field of rheology is crucial for understanding and controlling the physical properties of pharmaceutical formulations.
- Significant developments in pharmaceutical rheology have occurred since 1965, necessitating a comprehensive review.
Purpose of the Study:
- To review and synthesize significant advances in the rheology of pharmaceutical and allied materials since 1965.
- To provide a structured overview of rheological considerations for various pharmaceutical dosage forms.
Main Methods:
- A comprehensive literature review was conducted, analyzing 292 references.
- The review categorizes information based on material type and pharmaceutical application.
Main Results:
- Key advances in the rheology of powders, suspensions, semi-solids (creams, ointments), emulsions, suppositories, pessaries, and foam aerosols are detailed.
- The review highlights the evolution of understanding material properties and their impact on formulation performance.
Conclusions:
- This review consolidates a significant body of knowledge on pharmaceutical rheology over several decades.
- It serves as a valuable resource for researchers and formulators working with diverse pharmaceutical materials.