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Updated: Aug 2, 2026

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Published on: July 18, 2014
An unexpected tumor causing right ventricular obstruction
Jorge Padilla-Ibarra1, Hugo Rodríguez Zanella2, Roberto Cano Zarate3
1Cardiology Department, National Institute of Cardiology, "Ignacio Chávez, Mexico City, Mexico.
A soft tissue sarcoma patient developed dyspnea due to a right ventricular outflow tract mass. Multimodality imaging, including echocardiography and CTPA, was crucial for diagnosis, highlighting malignancy suspicion.
Area of Science:
- Cardiology
- Oncology
- Radiology
Background:
- A 58-year-old male with a history of soft tissue sarcoma in remission presented with progressive dyspnea.
- This symptom progression prompted further investigation into potential cardiac or pulmonary causes.
Observation:
- Transthoracic echocardiography revealed right ventricular dilation and a significant elevation in right ventricular systolic pressure (RVSP) to 110 mm Hg.
- A lobulated mass was identified within the right ventricular outflow tract (RVOT), causing obstruction.
- Microbubble contrast administration demonstrated perfusion within the mass, raising suspicion for malignancy.
Findings:
- CT pulmonary angiogram (CTPA) confirmed the RVOT mass but ruled out pulmonary embolism.
- The imaging findings collectively suggested a malignant mass within the right ventricular outflow tract.
Implications:
- This case underscores the utility of a multimodality imaging approach in diagnosing complex cardiac masses.
- Accurate and timely diagnosis of RVOT masses is critical for patient management and treatment planning.
- Integrating echocardiography and CTPA aids in differentiating benign from malignant etiologies in the RVOT.
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