Graphene as multifunctional delivery platform in cancer therapy

Area of Science:

• Biomedical Engineering
• Nanotechnology
• Materials Science

Background:

• Graphene-based nanomaterials are increasingly utilized in biomedical applications, particularly for drug and gene delivery.
• Their high surface area enables significant cargo loading capacity, enhancing therapeutic potential.
• Graphene's ability to improve drug efficacy without increasing dosage is crucial for cancer treatment.

Purpose of the Study:

• To review recent advancements in graphene-based drug and gene delivery systems for cancer therapy.
• To analyze the advantages and disadvantages of various graphene materials for effective cargo delivery.
• To discuss strategies for mitigating the cytotoxic effects of graphene oxide and creating biocompatible platforms.

Main Methods:

• Literature review of recent studies on graphene-based nanomaterials in drug and gene delivery.
• Analysis of graphene material properties relevant to biomedical applications.
• Evaluation of methods for enhancing biocompatibility and reducing cytotoxicity of graphene-based systems.

Main Results:

• Graphene nanomaterials demonstrate high cargo loading capacity for efficient drug and gene delivery.
• Graphene can enhance chemotherapeutic efficacy in cancer treatment.
• Various graphene-based materials offer distinct advantages and disadvantages for delivery systems.

Conclusions:

• Graphene-based nanomaterials represent a promising platform for advanced cancer therapy delivery systems.
• Further research is needed to optimize biocompatibility and minimize potential cytotoxic impacts.
• Continued development of graphene delivery systems holds significant potential for improving cancer treatment outcomes.