Related Experiment Video
Updated: Jun 23, 2026

07:41
Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
Published on: October 23, 2020
Visual impairment certification due to diabetic retinopathy in North and Eastern Devon
Siying Lin1, Bhaskar Gupta2, Natalee James3
1Torbay Hospital, Torbay and South Devon NHS Foundation Trust, Torquay, UK.
Acta Ophthalmologica
|April 4, 2017
Summary
Diabetic retinopathy (DR) caused certifications of visual impairment (CVI) comparable to other regions. Long-standing screening programs appear effective in preventing severe sight impairment from DR.
Area of Science:
- Ophthalmology
- Public Health
- Endocrinology
Background:
- Diabetic retinopathy (DR) is a leading cause of preventable blindness.
- Effective diabetic screening programs are crucial for early detection and intervention.
- Understanding the incidence of visual impairment due to DR informs public health strategies.
Purpose of the Study:
- To determine the incidence of certifications of visual impairment (CVI) specifically due to diabetic retinopathy (DR).
- To assess the impact of DR on visual impairment in a region with established diabetic screening since 1992.
- To compare DR-related CVIs with overall CVI data and analyze characteristics of affected individuals.
Main Methods:
- Retrospective review of all CVIs attributed to DR.
- Utilized mid-year population estimates and a diabetes prevalence model.
- Calculated annual incidence of DR-related CVI from 2010-2013 and compared 2013 data to all CVIs.
Main Results:
- 75 CVIs were attributed to DR (52 sight impaired, 23 severely sight impaired).
- DR was a cause in 4.3% of all CVIs in 2013; incidence ranged from 30.8-77.4 per million population.
- Mean age was 65.5 years with 22 years of known diabetes; 25% type 1, 75% type 2 diabetes.
Conclusions:
- The incidence of CVI due to DR in this region is comparable to international reports.
- Results suggest the long-standing retinal screening program is effective.
- DR was a significant cause of blindness but did not lead to SSI certifications in the working-age population studied.
Related Concept Videos
Photoreceptors and Visual Pathways
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Diabetic Foot Ulcer
Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...
Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Diabetic Neuropathy
DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...

