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Updated: Aug 19, 2026

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
Published on: April 11, 2018
Multiphysics of bone remodeling: A 2D mesoscale activation simulation
C Spingarn1, D Wagner1,2, Y Rémond1
1Laboratoire des Sciences de l'Ingenieur, de l'Informatique et de l'Imagerie (Icube), Université de Strasbourg, CNRS, 67000 Strasbourg, France.
Abstract:
In this work, we present an evolutive trabecular model for bone remodeling based on a boundary detection algorithm accounting for both biology and applied mechanical forces, known to be an important factor in bone evolution. A finite element (FE) numerical model using the Abaqus/Standard® software was used with a UMAT subroutine to solve the governing coupled mechanical-biological non-linear differential equations of the bone evolution model. The simulations present cell activation on a simplified trabeculae configuration organization with trabecular thickness of 200µm. For this activation process, the results confirm that the trabeculae are mainly oriented in the active direction of the principal mechanical stresses and according to the principal applied mechanical load directions. The trabeculae surface activation is clearly identified and can provide understanding of the different bone cell activations in more complex geometries and load conditions.
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