Jove
Visualize
Contact Us

Related Experiment Videos

Pulling angle-dependent force microscopy.

L Grebíková1, H Gojzewski1, B D Kieviet1

  • 1Materials Science and Technology of Polymers, MESA+, Institute of Nanotechnology, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands.

The Review of Scientific Instruments
|April 5, 2017
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Layer-by-Layer Printing of Photopolymers in 3D: How Weak is the Interface?

ACS applied materials & interfaces·2020
Same journal

A compact low-power magnetic particle imaging scanner based on a permanent-magnet field-free-line generator with high gradient.

The Review of scientific instruments·2026
Same journal

Achieving ultrahigh resolution with high efficiency: Optical design of the two-dimensional Resonant Inelastic X-ray Scattering (2D-RIXS) spectrometer at NanoTerasu beamline 02U.

The Review of scientific instruments·2026
Same journal

Automated laboratory x-ray diffractometer and fluorescence spectrometer for high-throughput materials characterization.

The Review of scientific instruments·2026
Same journal

Nonlinear Bayesian Doppler tomography for simultaneous reconstruction of flow and temperature.

The Review of scientific instruments·2026
Same journal

A Reflectance-based multimodal wearable photoplethysmography (PPG) sensor.

The Review of scientific instruments·2026
Same journal

Temporal analysis of products-Raman (TAP-Raman): An integrated setup for operando spectroscopy and transient kinetic analysis.

The Review of scientific instruments·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

This study introduces a new atomic force microscopy (AFM) method for 3D force control, enabling measurement of force direction. Experiments reveal angle-dependent desorption forces for single polymer chains, highlighting the technique's value.

Area of Science:

  • Materials Science
  • Surface Chemistry
  • Biophysics

Background:

  • Atomic Force Microscopy (AFM) traditionally measures forces normal to a surface.
  • Controlling force direction is crucial for understanding complex surface interactions.
  • Single-molecule force spectroscopy provides insights into polymer behavior.

Purpose of the Study:

  • To develop and demonstrate a method for three-dimensional (3D) displacement control in AFM force spectroscopy.
  • To investigate the angle-dependent desorption of single polymer chains from a surface.
  • To showcase the utility of directional force control in AFM experiments.

Main Methods:

  • Implemented a novel AFM technique for precise 3D force vector control.
  • Utilized single-molecule pull experiments with end-grafted poly(2-hydroxyethyl methacrylate) (PHEMA) chains.

Related Experiment Videos

  • Performed experiments in an aqueous solution on a planar silica surface.

    • Main Results:

    • Demonstrated successful control over both the magnitude and direction of applied forces.
    • Observed clear evidence of angular dependence in the desorption force of single PHEMA chains.
    • Quantified the force required to detach single polymer chains at various angles.

    Conclusions:

    • The developed 3D force control method significantly enhances AFM capabilities.
    • Single polymer chain desorption forces are demonstrably dependent on the pulling angle.
    • This technique offers valuable insights into polymer-surface interactions and material properties.