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Three-year survival in primary cardiac angiosarcoma
Naoto Fukunaga1, Takeshi Kitai, Yukihiro Imai
1Department of Cardiovascular surgery, Kobe City Medical Center General Hospital.
The Journal of Medical Investigation : JMI
|April 5, 2017
Summary
A rare cardiac angiosarcoma was diagnosed in an 18-year-old female. Despite treatment, the patient succumbed to metastatic angiosarcoma over three years post-surgery.
Area of Science:
- Cardiology
- Oncology
- Pathology
Background:
- Cardiac angiosarcoma is a rare and aggressive malignancy.
- Early diagnosis and treatment are crucial for patient outcomes.
Observation:
- An 18-year-old female presented with an immobile 4.6 cm×3.7 cm cardiac mass.
- Echocardiography revealed the mass occupying the right atrial chamber and invading the tricuspid valve annulus.
- Surgical exploration showed the mass protruding from the right atrial appendage and adhering to the pericardium.
Findings:
- Histological examination confirmed cardiac angiosarcoma.
- Immunohistochemical staining was positive for CD34 and CD31.
- The patient received radiochemotherapy following surgical resection.
Implications:
- This case highlights the aggressive nature of cardiac angiosarcoma, even in young, otherwise healthy individuals.
- Despite aggressive treatment, metastasis remains a significant challenge, underscoring the need for novel therapeutic strategies.
- Further research into the pathogenesis and treatment of cardiac angiosarcoma is warranted.