Postoperative roll cake-like macular fold after retinal detachment surgery
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Updated: Aug 16, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
Ryusaburo Mori1, Hiroyuki Nakashizuka2, Yumiko Machida1
1Division of Ophthalmology, Department of Visual Sciences, Nihon University Hospital, Nihon University School of Medicine, 1-6, Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-8301, Japan.
Purpose:
To report a case developing a severe retinal fold (RF), resembling a roll cake on optical coherence tomography (OCT), after retinal detachment (RD) surgery.
Case Report:
A 61-year-old man underwent vitrectomy for a limited macula-on-superior rhegmatogenous RD and gas tamponade at another hospital. Despite remaining prone for 4 days, RF was noted after gas disappearance and he was referred to us. OCT showed a roll cake-like RF, which resolved after vitrectomy with internal limiting membrane (ILM) peeling, creation of a new detachment, perfluorocarbon liquid injection, air-fluid exchange, silicone oil tamponade and prone positioning.
Conclusion:
ILM peeling including the area of the retinal fold, followed by new detachment creation and finally perfluorocarbon liquid injection, effectively flattened the severe RF. To our knowledge, this is the most severe case of RF to be documented by OCT and illustrates that broad ILM peeling, including the RF, is effective for treating RF.

