Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

AK, PGM1 and 6PGD polymorphisms in Central Sardinia.

R F Masala1, M Lunesu, M S Ristaldi

  • 1Dipartimento Biologia Sperimentale, Università di Cagliari, Italy.

Human Heredity
|January 1, 1988
PubMed
Summary

This study analyzed adenylate kinase (AK), phosphoglucomutase (PGM1), and 6-phosphogluconate dehydrogenase (6PGD) gene variants in Central Sardinia. Findings provide population genetics data for these enzymes in an Italian demographic group.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genetic structure of southwestern Corsica (France).

American journal of human biology : the official journal of the Human Biology Council·2017
Same author

Non-random distribution of 17 Y-chromosome STR loci in different areas of Sardinia.

Forensic science international. Genetics·2014
Same author

Analysis of a genetic isolate: the case of Carloforte (Italy).

Human biology·2013
Same author

Efficacy of specific bioelectrical impedance vector analysis (BIVA) for assessing body composition in the elderly.

The journal of nutrition, health & aging·2013
Same author

Genetic markers and explosive leg-muscle strength in elite Italian soccer players.

The Journal of sports medicine and physical fitness·2012
Same author

Nutritional and psycho-functional status in elderly patients with Alzheimer's disease.

The journal of nutrition, health & aging·2012

Area of Science:

  • Population genetics
  • Biochemical genetics
  • Human genetics

Background:

  • Genetic polymorphisms provide insights into population history and diversity.
  • Adenylate kinase (AK), phosphoglucomutase (PGM1), and 6-phosphogluconate dehydrogenase (6PGD) are enzymes with known genetic variations.
  • Understanding enzyme gene frequencies is crucial for anthropological and medical studies.

Purpose of the Study:

  • To investigate the gene frequencies of AK, PGM1, and 6PGD in a Central Sardinian population.
  • To compare these frequencies with those reported in other Italian populations.
  • To contribute to the genetic characterization of Sardinian and Italian populations.

Main Methods:

  • Analysis of adenylate kinase (AK), phosphoglucomutase (PGM1), and 6-phosphogluconate dehydrogenase (6PGD) polymorphisms.

Related Experiment Videos

  • Genotyping of individuals from Central Sardinia.
  • Calculation of gene frequencies for each polymorphism.
  • Comparative analysis with existing population data.

    • Main Results:

    • Gene frequencies determined for AK1 (0.973), PGM1(1) (0.842), and PGDA (0.969) in the Central Sardinian sample.
    • Observed frequencies provide a genetic profile for these enzymes in the study population.
    • Data allows for regional comparisons within Italy.

    Conclusions:

    • The study establishes baseline gene frequencies for AK, PGM1, and 6PGD in Central Sardinia.
    • Comparison with other Italian populations may reveal genetic differentiation or similarities.
    • These findings enhance the understanding of human genetic variation in the Mediterranean region.