Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cyclic (Alkyl)(amino)carbenes (CAACs): Recent Developments.

Mohand Melaimi1, Rodolphe Jazzar1, Michèle Soleilhavoup1

  • 1UCSD-CNRS Joint Research Chemistry Laboratory, UMI 3555, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, 92093-0358, USA.

Angewandte Chemie (International Ed. in English)
|April 5, 2017
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Three-State Electrochiroptical Switches Derived from Chiral Stable Carbenes.

Journal of the American Chemical Society·2026
Same author

Generation of mono(amino)carbenes from <i>N</i>-triftosyl amino hydrazonates with blue light.

Chemical communications (Cambridge, England)·2026
Same author

Organocatalysis promoted by 1,2,3-triazolylidenes (MICs): carbenes which make a difference.

Chemical Society reviews·2025
Same author

<i>N</i>-hydrazine cyclic(amino)(alkyl)carbene ruthenium complexes: synthesis and reactivity in olefin metathesis.

Chemical communications (Cambridge, England)·2025
Same author

The Genuine Carbene Conundrum.

Chemistry (Weinheim an der Bergstrasse, Germany)·2025
Same author

Switching mesoionic carbene-organocatalysis from radical to ionic pathway through base-controlled formation of Breslow intermediates <i>versus</i> Breslow enolates.

Chemical science·2025

Cyclic (alkyl)(amino)carbenes (CAACs) are highly nucleophilic and electrophilic stable carbenes. These versatile compounds activate small molecules, stabilize reactive species, and form robust catalysts, with recent advances highlighted.

Area of Science:

  • Organometallic Chemistry
  • Main-Group Chemistry
  • Catalysis

Background:

  • Cyclic (alkyl)(amino)carbenes (CAACs), discovered in 2005, are a class of stable carbenes.
  • CAACs exhibit exceptional nucleophilicity (σ-donation) and electrophilicity (π-acceptance).

Purpose of the Study:

  • To review the significant advancements in CAAC chemistry.
  • To highlight findings reported in the last three years, building upon earlier results up to 2013.

Main Methods:

  • Literature review focusing on CAAC applications and properties.
  • Summary of key findings from 2005 to 2013, with emphasis on recent research.

Main Results:

  • CAACs effectively activate small molecules and strong bonds.
Keywords:
carbenescyclic (alkyl)(amino)carbenes (CAACs)homogeneous catalysistransition metals

Related Experiment Videos

  • They stabilize highly reactive main-group and transition-metal species.
  • CAACs form strong bonds with metal centers, leading to robust catalysts.

    • Conclusions:

    • CAACs are versatile ligands with broad applications in chemistry.
    • Their unique electronic properties enable diverse chemical transformations.
    • Recent research continues to expand the utility of CAACs in catalysis and stabilization.