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Lynch Syndrome and Endometrial Cancer
Sareena Singh1, Kimberly E Resnick1
1From the Department of OB/GYN, Division of Gynecologic Oncology, MetroHealth Medical Center, Cleveland, Ohio.
Southern Medical Journal
|April 5, 2017
Abstract:
In patients with Lynch syndrome, gynecologic cancer often can be the first presenting malignancy. In this review, we summarize the genetics of Lynch syndrome and review the various modalities of identifying patients at risk for this syndrome. The clinical characteristics of Lynch-associated endometrial cancer and screening and risk-reducing strategies also are described.