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Trigeminal Neuralgia: Toward a Multimodal Approach
Alfio Spina1, Pietro Mortini1, Federica Alemanno2
1Department of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Vita-Salute University, Milan, Italy.
World Neurosurgery
|April 6, 2017
Summary
Trigeminal neuralgia (TN) treatments can be ineffective long-term, leading to chronic pain. A personalized, multimodal approach is needed, considering neuropsychological factors for better outcomes.
Area of Science:
- Neurology
- Pain Management
Background:
- Trigeminal neuralgia (TN) is a common cranial neuralgia, affecting women more than men.
- Current treatments like antiepileptic drugs and microvascular decompression have limitations, with over 50% experiencing pain recurrence.
- Chronic TN significantly impacts quality of life, causing anxiety and depression.
Purpose of the Study:
- To review the efficacy and safety of current Trigeminal neuralgia treatments.
- To propose a multimodal treatment approach for chronic Trigeminal neuralgia patients.
Main Methods:
- Review of current Trigeminal neuralgia treatment modalities.
- Analysis of pain evaluation systems and neuropsychological features in Trigeminal neuralgia.
Main Results:
- Current treatment options for Trigeminal neuralgia were reviewed.
- Pain evaluation and neuropsychological aspects were analyzed to inform treatment algorithms.
Conclusions:
- Chronic pain in Trigeminal neuralgia can alter self-perception and treatment outcomes.
- A personalized, multimodal treatment strategy is essential, integrating neuropsychological considerations.

