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[A multislice gradient-echo sequence for contrast medium-enhanced MR diagnosis of intracranial tumors]
W Schörner1, B Sander, W Kornmesser
1Radiologische Klinik und Poliklinik, Klinikum Rudolf Virchow, Freie Universität Berlin.
Abstract:
A multislice gradient echo sequence (FLASH) was compared with a conventional spin-echo (SE) technique with regard to its value for contrast enhanced MR diagnosis. In 28 patients with cerebral tumours, SE images (SE 400/30; four images/3.4 minutes) and FLASH images (FLASH 315/14; 15 images/1.4 minutes) were obtained before and after gadolinium DTPA. After gadolinium-DTPA results were comparable for both techniques with respect to contrast enhancement, tumor contrast and delineation. Because of the higher efficiency of the FLASH 315/14 technique, this sequence is the method of choice for contrast enhanced cerebral MR imaging.
Insights
Gradient echo sequences (FLASH) offer efficient, comparable contrast enhancement for brain tumor diagnosis compared to spin-echo (SE) techniques. FLASH is recommended for contrast-enhanced brain MRI due to its speed.
Area of Science:
- Radiology
- Medical Imaging
- Neurology
Background:
- Contrast-enhanced Magnetic Resonance Imaging (MRI) is crucial for diagnosing cerebral tumors.
- Conventional spin-echo (SE) sequences are widely used but can be time-consuming.
Purpose of the Study:
- To compare the diagnostic value of multislice gradient echo (FLASH) sequences with conventional spin-echo (SE) techniques for contrast-enhanced MRI of cerebral tumors.
Main Methods:
- A multislice gradient echo sequence (FLASH 315/14) and a conventional spin-echo sequence (SE 400/30) were utilized.
- Images were acquired in 28 patients with cerebral tumors before and after gadolinium DTPA administration.
- Image acquisition times were compared: 15 images in 1.4 minutes for FLASH versus 4 images in 3.4 minutes for SE.
Main Results:
- Both SE and FLASH techniques provided comparable results regarding contrast enhancement, tumor contrast, and delineation after gadolinium DTPA administration.
- The FLASH sequence demonstrated significantly higher efficiency, acquiring more images in a shorter time frame.
Conclusions:
- The FLASH sequence is the preferred method for contrast-enhanced cerebral MRI due to its superior efficiency.
- Gradient echo techniques like FLASH offer a valuable alternative for rapid and effective brain tumor diagnosis.