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Difluorocarbene transfer from a cobalt complex to an electron-deficient alkene
Monalisa Goswami1, Bas de Bruin, Wojciech I Dzik
1Homogeneous, Supramolecular and Bio-Inspired Catalysis, Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands. W.I.Dzik@uva.nl b.debruin@uva.nl.
Chemical Communications (Cambridge, England)
|April 6, 2017
Abstract:
We report the synthesis of the trifluoromethyl cobalt(iii)tetraphenylporphyrinato complex [Co(TPP)CF3], which loses fluoride upon one-electron reduction and transfers a difluorocarbene moiety to n-butyl acrylate to produce the corresponding gem-difluorocyclopropane. Catalytic CF2 transfer from Me3SiCF3 to n-butyl acrylate becomes possible when directly using the divalent cobalt(ii) porphyrin catalysts in the presence of NaI.