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A chiral, porous, organic cage-based, enantioselective potentiometric sensor for 2-aminobutanol
Ai-Hong Duan1, Bang-Jin Wang1, Sheng-Ming Xie1
1Department of Chemistry, Yunnan Normal University, Kunming, People's Republic of China.
Abstract:
A new enantioselective potentiometric sensor containing R-type chiral porous organic cage CC9 as the chiral selector was designed for the assay of 2-aminobutanol. Optimized membrane electrodes displayed a linear dynamic range from 10-3 ~ 10-1 mol·L-1 with a detection limit of 2.5 × 10-4 mol·L-1 and a Nernstian response of 27 ± 0.5mV·decade-1 toward S-2-aminobutanol within the pH range 7.0-10.0. The potentiometric enantioselectivity coefficient ( logKS,RPot) of this sensor was -1.333, indicating that the porous organic cage-based electrode exhibited good discrimination toward S-2-aminobutanol over R-2-aminobutanol.
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