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N-myc amplified in retinoblastoma cell line FMC-RB1
R Seshadri1, C Matthews, M D Norris
1Department of Haematology, Flinders Medical Centre, Bedford Park, South Australia.
Cancer Genetics and Cytogenetics
|July 1, 1988
Abstract:
A recently described retinoblastoma cell line, FMC-RB1, showed a 16-fold N-myc oncogene amplification. The patient from whom the cell line was obtained died from an aggressive disease. It is suggested that N-myc amplification may be an adverse prognostic indicator.