Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The Boston keratoprosthesis.

Hajirah N Saeed1, Swapna Shanbhag, James Chodosh

  • 1Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.

Current Opinion in Ophthalmology
|April 7, 2017
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Type I to type II Boston keratoprosthesis exchange: a report of two patients.

BMC ophthalmology·2026
Same author

Pediatric Keratoprosthesis with Pars Plana Vitrectomy: Promise and Peril.

Cornea·2026
Same author

Factors influencing clinical research participation in ophthalmology: a mixed-methods study in keratoconus.

Scientific reports·2026
Same author

Clonal cytotoxic CD8<sup>+</sup> T-cell expansion and HLA-B44 supertype association in bupropion-induced severe cutaneous adverse reactions.

The Journal of investigative dermatology·2026
Same author

Amniotic membrane in ophthalmology: Historical perspectives, biological properties, and clinical applications.

Progress in retinal and eye research·2026
Same author

Intermediate Term Results of a Novel Minimally Invasive Keratoprosthesis.

Ophthalmology science·2026

The Boston keratoprosthesis (BKPro) offers improved visual outcomes and device retention for severe corneal disease. Advances in surgical techniques and patient care have broadened BKPro indications, making it a viable option even after failed transplants.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Biomaterials in Medicine

Background:

  • The Boston keratoprosthesis (BKPro) is a critical treatment for severe corneal disease when traditional transplants fail.
  • Since its FDA approval in 1992, the BKPro has undergone significant design, surgical, and postoperative care advancements.
  • These improvements have expanded its use and reduced complications, enhancing its role in visual rehabilitation.

Purpose of the Study:

  • To review the current indications for BKPro implantation.
  • To summarize management strategies and outcomes associated with BKPro.
  • To highlight recent advances in BKPro technology and application.

Main Methods:

  • Literature review of studies on Boston keratoprosthesis (BKPro).

Related Experiment Videos

  • Analysis of long-term data on device retention and visual outcomes.
  • Evaluation of comparative effectiveness against traditional corneal transplantation.

    • Main Results:

    • Modified BKPro devices and perioperative care have improved device retention and visual results.
    • BKPro shows potential superiority over traditional transplants, especially in cases with prior graft failure.
    • Earlier BKPro implantation may be beneficial for certain conditions without increasing complication risks.

    Conclusions:

    • The clinical indications for BKPro implantation are expanding beyond its initial 'last resort' status.
    • Prompt identification and management of postoperative complications are crucial for preserving vision.
    • Ongoing advancements continue to enhance the efficacy and applicability of the BKPro.