Related Experiment Videos
[Retinopathy of prematurity].
1Service d'ophtalmologie, centre EVICR.net APOCHU 86, centre hospitalier universitaire Amiens Picardie, 80054 Amiens cedex 1, France; Université de Picardie-Jules-Verne, chemin du Thil, 80025 Amiens, France.
Journal Francais D'Ophtalmologie
|April 8, 2017
Summary
Retinopathy of prematurity (ROP) is a serious eye condition in premature infants. Early screening and treatment are crucial to prevent vision loss and blindness.
Area of Science:
- Ophthalmology
- Neonatology
- Pediatrics
Background:
- Retinopathy of prematurity (ROP) is a vasoproliferative disorder affecting extremely preterm infants.
- Exposure to high oxygen concentrations during therapy is a primary risk factor.
- ROP stems from immature peripheral retinal vessels at premature birth.
Purpose of the Study:
- To outline the screening, classification, and management of retinopathy of prematurity.
- To emphasize the importance of regular fundus examinations for at-risk infants.
Main Methods:
- Systematic dilated fundus examinations for infants born before 32 post-menstrual weeks or weighing <1500g.
- Classification based on ROP zone, clock hours, stage, and presence of "plus" disease.
- Treatment guided by "threshold disease" and "type 1 pre-threshold disease" criteria.
Main Results:
- A majority of ROP cases resolve spontaneously.
- Laser ablation or cryotherapy are standard treatments for high-risk cases.
- Intravitreal VEGF inhibitors are under investigation as a therapeutic option.
Conclusions:
- Prompt screening and timely intervention are vital for preventing severe visual impairment and blindness in premature infants.
- Regular follow-up until complete retinal vascularization is essential for all infants, treated or not.