Related Experiment Video
Updated: Aug 16, 2026

Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells
Published on: February 3, 2011
Umbilical Cord Blood Natural Killer Cells, Their Characteristics, and Potential Clinical Applications
Anushruti Sarvaria1, Dunia Jawdat2, J Alejandro Madrigal1
1Anthony Nolan Research Institute, London, UK; Cancer Institute, University College London, London, UK.
Abstract:
Natural killer (NK) cells are lymphocytes of the innate immune system able to kill different targets such as cancer cells and virally infected cells without prior activation making then attractive candidates for cancer immunotherapy. Umbilical cord blood (UCB) has become a source of hematopoietic stem cells for transplantation but as we gain a better understanding of the characteristics of each immune cell that UCB contains, we will also be able to develop new cell therapies for cancer. In this review, we present what is currently known of the phenotype and functions of UCB NK cells and how these cells could be used in the future for cancer immunotherapy.
Related Concept Videos
Regulation of Hematopoietic Stem Cells
Stem Cell Culture
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Cytotoxic T Cells-mediated Immune Response
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...

