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Published on: January 7, 2019
An Unusual Presentation of Limited Granulomatosis with Polyangiitis Involving Vagina and Urethra
Sandra Soro Marín1, Enrique Júdez Navarro2, Manuela Sianes Fernández2
1Rheumatology Unit, Hospital General de Villarrobledo, Villarrobledo, Albacete, Spain.
Abstract:
Granulomatosis with polyangiitis (GPA) is a systemic necrotizing granulomatosis vasculitis characterized by predilection to affect small- and medium-sized blood vessels and commonly affects the upper and lower respiratory tract and kidneys in most cases. Genital involvement is reported in <1% of cases in large cohorts and nearly all cases have been in the setting of multisystemic disease or during the course of the disease in patients already diagnosed as GPA. A case is presented of uncommon limited urogenital GPA in a 66-year-old woman with an irregular mass occupying urethra and vagina. The patient showed a good response after Corticoids and Methotrexate.
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