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Published on: September 26, 2016
[Pseudotumoral pelvic actinomycosis : one should think of it]
A Kakkos1, E Gonne2, C Coimbra3
1Service de Gynécologie- Obstétrique, CHU de Liège, Site Sart Tilman, Belgique.
Abstract:
Actinomycosis is a rare chronic disease caused by a group of anaerobic Gram positive bacteria. It may mimic a neoplasia at various anatomical levels. A pelvic localization is exceptional but has an increasing incidence since the use of intrauterine devices. In such cases, pelvic actinomycosis may present as a gynecological or a lower colonic malignancy. For all atypical clinical, with a prominent infectious or inflammatory context, the diagnosis of actinomycosis must be suggested and discussed with the pathologist to whom the biopsy will be submitted. In the absence of a preoperative diagnosis, an inadequately aggressive pelvic surgery might be performed and rendered particularly complex due to the adherent and diffusely inflammatory pattern of the disease. The treatment of choice remains a long-term therapy with antibiotics that leads to a complete clinical and radiological response in the majority of cases. We report the case of a 27-year-old woman with a clinical and radiological diagnosis of rectal carcinoma but with limited preoperative biopsy that revealed a pelvic actinomycosis and allowed a conservative and successful antibacterial treatment.
Insights
Pelvic actinomycosis, a rare bacterial infection, can mimic cancer. Early diagnosis through biopsy is crucial for effective antibiotic treatment, avoiding unnecessary surgery.
Area of Science:
- Microbiology
- Pathology
- Gynecology
Background:
- Actinomycosis is a rare, chronic infection caused by anaerobic Gram-positive bacteria.
- It can mimic neoplastic conditions at various anatomical sites.
- Pelvic actinomycosis, though exceptional, is increasingly reported, often associated with intrauterine device use.
Observation:
- Pelvic actinomycosis can present as gynecological or lower colonic malignancy.
- Atypical clinical presentations with infectious or inflammatory contexts warrant consideration of actinomycosis.
- Preoperative diagnosis is vital to prevent aggressive surgery due to the disease's inflammatory nature.
Findings:
- A 27-year-old woman presented with clinical and radiological signs of rectal carcinoma.
- Limited preoperative biopsy revealed pelvic actinomycosis, not malignancy.
- This diagnosis enabled a conservative, successful antibacterial treatment approach.
Implications:
- Suggesting actinomycosis in atypical pelvic cases with infectious/inflammatory signs is critical.
- Collaboration between clinicians and pathologists is essential for accurate diagnosis.
- Long-term antibiotic therapy is the mainstay treatment, leading to favorable outcomes.
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