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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...

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Related Experiment Video

Updated: Jul 27, 2026

Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice
09:01

Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice

Published on: March 10, 2015

[How I explore … Crohn's disease by various imaging modalities].

C Desir1, C Coimbra2, M Decker2

  • 1Service de Radiologie, CHU de Liège, Site Sart Tilman, Liège, Belgique.

Revue Medicale De Liege
|April 8, 2017
PubMed
Summary

Crohn

Keywords:
DiagnosisFollowImaging techniquesCrohn’s diseaseup

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Area of Science:

  • Gastroenterology and Hepatology
  • Medical Imaging
  • Radiology

Background:

  • Crohn's disease causes chronic intestinal inflammation and structural damage.
  • Symptoms poorly correlate with lesion severity, necessitating objective monitoring.
  • Current imaging guidelines lack consensus on the optimal modality.

Purpose of the Study:

  • To evaluate cross-sectional imaging techniques for assessing Crohn's disease activity.
  • To determine the most effective imaging modality for diagnosis and follow-up.
  • To highlight the role of non-radiating imaging in managing Crohn's disease.

Main Methods:

  • Review of current imaging modalities including ultrasonography, MRI, and CT.
  • Emphasis on non-radiating techniques like ultrasonography and MRI.
  • Comparison of imaging capabilities for assessing disease activity and damage.

Main Results:

  • Ultrasonography and MRI are preferred non-radiating modalities.
  • CT (Tomodensitometry) is reserved for emergency situations.
  • Entero-MRI emerges as the standard for Crohn's disease diagnosis and monitoring.

Conclusions:

  • Entero-MRI offers superior contrast resolution for accurate Crohn's disease assessment.
  • Imaging is crucial for evaluating disease activity, treatment response, and complications.
  • Non-radiating modalities like MRI and ultrasonography are key for safe, effective Crohn's disease management.