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[Malignant phyllodes tumour : a case report].

J Radermacher1, O Burlet2, R M Sylvestre3

  • 1Service d'Anatomie et Cytologie pathologique, CHU de Liège, Site du Sart Tilman, 4000 Liège, Belgique.

Revue Medicale De Liege
|April 8, 2017
PubMed
Summary
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A rare malignant phyllodes tumor with rhabdomyosarcomatous features was diagnosed in a young woman after breast trauma. This case highlights the importance of considering unusual diagnoses in post-traumatic breast lesions.

Area of Science:

  • Oncology
  • Pathology
  • Radiology

Background:

  • Phyllodes tumors are rare breast neoplasms, accounting for up to 1% of all mammary cancers.
  • Malignant phyllodes tumors comprise 10-20% of all phyllodes tumors and exhibit distinct behavior compared to common breast cancers.

Observation:

  • A 28-year-old woman presented with a month-long history of post-traumatic swelling in her left breast.
  • Ultrasonography revealed a 9 cm, well-defined, hypoechoic lesion.
  • Initial surgical hypothesis was hematoma, but pathological analysis confirmed a malignant phyllodes tumor with heterologous rhabdomyosarcomatous differentiation.

Findings:

  • The malignant phyllodes tumor showed no evidence of metastasis.
  • The patient underwent radical mastectomy followed by adjuvant radio-chemotherapy.
Keywords:
Breast cancerMalignant phyllodes tumourRhabdomyosarcoma

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Implications:

  • This case underscores the importance of thorough pathological evaluation of breast lesions, especially those with a history of trauma.
  • The atypical presentation necessitates a discussion on the classification and management strategies for malignant phyllodes tumors.
  • Understanding the unique behavior of these tumors is crucial for effective patient treatment and prognosis.