Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fungal Biofilms: Inside Out.

Katherine Lagree1, Aaron P Mitchell1

  • 1Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213.

Microbiology Spectrum
|April 8, 2017
PubMed
Summary

This study explores the internal mechanisms of biofilms, including gene regulation and environmental factors. It connects these internal processes to the biofilm's structure, development, and medical significance.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quality, Cost, and Timeliness of Cancer Treatment in Medicare Advantage and Traditional Medicare.

JAMA internal medicine·2026
Same author

Timeliness of Prostate Cancer Treatment in Medicare Advantage and Traditional Medicare: More Similarities than Differences?

JCO oncology practice·2026
Same author

Shared antibiofilm targets of biofilm regulators Wor3 and Bcr1 in Candida albicans.

Genetics·2026
Same author

Negative control of Candida albicans biofilm formation by combined action of white-opaque regulator Wor2 and biofilm regulator Bcr1.

G3 (Bethesda, Md.)·2026
Same author

When Priority Review No Longer Prioritizes.

JCO oncology practice·2026
Same author

Use of Low-Value Cancer Care in Practices Acquired by Private Equity Firms.

Journal of the National Cancer Institute·2026

Area of Science:

  • Microbiology
  • Molecular Biology
  • Biophysics

Background:

  • Biofilms are complex microbial communities with significant medical and industrial relevance.
  • Understanding the internal workings of biofilms is crucial for controlling their development and impact.
  • Current research often focuses on either internal processes or external structures, with limited integration.

Purpose of the Study:

  • To provide a comprehensive overview of the internal aspects of biofilms.
  • To link the intracellular environment and genetic regulation to observable biofilm characteristics.
  • To bridge the gap between molecular mechanisms and the macroscopic properties of biofilms.

Main Methods:

  • Review and synthesis of diverse investigative approaches.
  • Analysis of genetic determinants and transcriptional regulation within biofilms.
  • Examination of environmental factors influencing biofilm phenotypes.

Main Results:

  • Detailed exploration of individual biofilm phenotypes and their environmental drivers.
  • Elucidation of genetic underpinnings and regulatory networks governing biofilm formation.
  • Connection of internal biofilm dynamics to external structural and developmental features.

Conclusions:

  • A unified understanding of biofilm formation requires integrating internal molecular mechanisms with external structural and functional attributes.
  • This integrated perspective is essential for developing novel strategies to combat biofilm-related infections and industrial issues.
  • Future research should focus on interdisciplinary approaches to fully unravel biofilm complexity.

Related Experiment Videos