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Related Experiment Videos

Advances in Skin Regeneration Using Tissue Engineering.

Komal Vig1, Atul Chaudhari2, Shweta Tripathi3

  • 1Center for Nanobiotechnology Research, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA. komalvig@alasu.edu.

International Journal of Molecular Sciences
|April 8, 2017
PubMed
Summary

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This summary is machine-generated.

Tissue engineered skin substitutes are advancing rapidly, using diverse materials for wound healing. Current research aims for fully functional, vascularized skin grafts with improved usability and affordability.

Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Wound Healing Research

Background:

  • Tissue engineered skin substitutes have significantly advanced for wound healing applications.
  • Development involves artificial and natural materials, including acellular matrices and various biological sources (autologous, allograft, xenogenic, synthetic).

Purpose of the Study:

  • To provide an overview of recent advances in tissue engineered skin substitute development.
  • To discuss the availability and applications of different types of engineered skin substitutes.
  • To highlight ongoing research needs for improved skin substitute functionality and commercial viability.

Main Methods:

  • Review of current literature on tissue engineered skin substitute development.
  • Analysis of materials and sources used in engineered skin substitutes.
Keywords:
skin regenerationskin substitutestissue engineering

Related Experiment Videos

  • Evaluation of advantages and disadvantages of existing skin substitute technologies.

    • Main Results:

    • Diverse engineered skin substitutes exist, derived from acellular materials or synthesized from various biological and synthetic sources.
    • Each substitute type presents unique benefits and limitations.
    • A complete, fully functional skin substitute that rapidly vascularizes remains unavailable.

    Conclusions:

    • Continued research is essential to develop competent, full-thickness skin substitutes with rapid vascularization.
    • There is a critical need to redesign current substitutes for enhanced user-friendliness, commercial affordability, and extended shelf life.
    • Further innovation is required to meet the clinical demand for effective and accessible skin regeneration solutions.