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Strategies and Methodologies for Developing Microbial Detoxification Systems to Mitigate Mycotoxins.

Yan Zhu1, Yousef I Hassan2, Dion Lepp3

  • 1Guelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, ON N1G5C9, Canada. yan.zhu@agr.gc.ca.

Toxins
|April 8, 2017
PubMed
Summary

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This review explores microbiological strategies for mitigating mycotoxins, harmful fungal metabolites in food and feed. It details methods for developing effective biological detoxification solutions to protect livestock and human health.

Area of Science:

  • Agricultural Science
  • Microbiology
  • Food Safety

Background:

  • Mycotoxins contaminate global agricultural commodities, causing significant economic losses and posing health risks.
  • Biological detoxification offers an environmentally sound, safe, and efficient alternative to traditional methods for mycotoxin mitigation.

Purpose of the Study:

  • To review and assess research strategies for developing microbiological solutions for mycotoxin detoxification.
  • To provide a comprehensive understanding of the methodologies involved in each phase of this development process.

Main Methods:

  • Screening microbial consortia from natural sources.
  • Isolating and identifying single microbial strains with biotransformation capabilities.
  • Investigating strain physiology, identifying biotransformation products, assessing toxicity, and purifying enzymes.
Keywords:
biodegradationbiotransformationdetoxificationenzymemicroorganism identificationmycotoxin

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Main Results:

  • The review synthesizes current research approaches for mycotoxin mitigation using microorganisms.
  • It highlights the challenges and necessary steps in developing effective microbial detoxification strategies.

Conclusions:

  • A thorough understanding and application of the discussed methodologies are crucial for advancing novel microbiological solutions for mycotoxin detoxification.
  • This approach aids in developing safer and more efficient feed and food production processes.