Related Experiment Video
Updated: Aug 3, 2026
10:38
Large-scale Production of Recombinant RNAs on a Circular Scaffold Using a Viroid-derived System in Escherichia coli
Published on: November 30, 2018
An Unchartered Journey for Ribosomes: Circumnavigating Circular RNAs to Produce Proteins
Deirdre C Tatomer1, Jeremy E Wilusz1
1Department of Biochemistry & Biophysics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Molecular Cell
|April 8, 2017
Abstract:
In this issue of Molecular Cell, Legnini et al. (2017) and Pamudurti et al. (2017) demonstrate that endogenous circular RNAs may generate proteins, thereby expanding the eukaryotic proteome and revealing novel modes of cap-independent translation.
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