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Genome and Epigenome Maintenance by Keeping Histone Turnover in Check
1Laboratory of Epigenome Integrity, Epigenetics & Cell Fate Centre, UMR 7216 CNRS/Université Paris Diderot, 35 rue Hélène Brion, 75205 Paris Cedex 13, France.
Molecular Cell
|April 8, 2017
Abstract:
In this issue of Molecular Cell, Taneja et al. (2017) uncover a dual role for the conserved chromatin remodeler Fft3 in the maintenance of silent heterochromatin and the suppression of replication barriers at euchromatic loci through controlled histone turnover.