Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Miniaturized platform for high-throughput screening of stem cells.

Tina Tronser1, Anna A Popova1, Pavel A Levkin2

  • 1Karlsruhe Institute of Technology (KIT), Institute of Toxicology and Genetics (ITG), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany.

Current Opinion in Biotechnology
|April 8, 2017
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ultra-High-Throughput Discovery of Multifunctional Polyphenolic Coatings on Droplet Microarrays.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

S-Methylmethionine (Vitamin U): A Critical Narrative Review of Pharmacological Mechanisms, Evidence Levels, and Translational Barriers.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Functional Precision Oncology Approach Using Nanoliter Droplet Array for Drug Sensitivity Testing in Lung Cancer.

Advanced healthcare materials·2026
Same author

Intraspecific Variation in Drought and Nitrogen-Stress Responses in Pedunculate Oak (<i>Quercus robur</i> L.) Half-Sib Progeny.

Plants (Basel, Switzerland)·2025
Same author

Solid Medium Droplet Microarray for Miniaturized Antimicrobial Susceptibility Test.

Small science·2025
Same author

Multiplexed Fluorescent Microarrays on MIL-101(Cr) Thin Films as Luminescent Probes for pH and Disease-Associated Molecules.

Small (Weinheim an der Bergstrasse, Germany)·2025

Miniaturized platforms are crucial for high-throughput screening (HTS) of stem cells, addressing limitations in cell availability. This review explores recent advancements in these HTS systems for stem cell research.

Area of Science:

  • Stem cell biology
  • Regenerative medicine
  • Biotechnology

Background:

  • Stem cells possess self-renewal and differentiation potential, driving interest in clinical research and regenerative medicine.
  • Maintaining stemness and controlling differentiation in vitro remains a significant challenge, limiting their therapeutic applications.
  • High-throughput screening (HTS) aids in understanding stem cell fate and identifying stemness-maintaining factors.

Purpose of the Study:

  • To review recent advancements in miniaturized platforms for high-throughput screening (HTS) of stem cells.
  • To present novel designs of miniaturized HTS systems for stem cell research.
  • To address the limitations of traditional microtiter plates in stem cell HTS due to cell availability.

Main Methods:

Related Experiment Videos

  • Review of recent literature on miniaturized platforms for stem cell HTS.
  • Analysis of novel designs and technologies in microfluidic and other miniaturized HTS systems.
  • Discussion of the advantages of miniaturized platforms over conventional methods.

    • Main Results:

    • Significant progress has been made in developing miniaturized platforms for stem cell HTS.
    • Novel designs offer improved efficiency and reduced reagent/cell consumption.
    • These platforms overcome limitations associated with limited stem cell availability and expandability.

    Conclusions:

    • Miniaturized platforms are essential for advancing stem cell research and drug discovery.
    • The development of novel HTS systems is critical for overcoming current bottlenecks in the field.
    • Future research should focus on further optimizing these platforms for broader stem cell applications.