Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Membrane Fluidity01:23

Membrane Fluidity

Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.Fatty acids tails of phospholipids can be either saturated or...
Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at the...
Surface Membrane Barriers01:18

Surface Membrane Barriers

The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biofilm-Activated Enzymatic Biofuel Cell-Based Self-Powered Wound Dressing.

ACS nano·2026
Same author

Non-Superacid-Catalyzed Preparation of Anion Exchange Membranes for High-Performance Water Electrolyzers.

Angewandte Chemie (International ed. in English)·2026
Same author

Shear-Stiffening Damping Ionogels Enabled by the Synergy of Dynamic Bonds and Steric Hindrance.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Bio-Ionic Liquid-Induced Rapid Self-Initiating Tough Ionogels for In Situ Adhesion.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Upcycling Waste PET Into Ionic Liquid-Derived Small-Molecule Adhesives.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Spontaneous, Catalyst-Free Co-Polymerization of Ionic Liquids With CO<sub>2</sub> Toward Polycarbonate.

Angewandte Chemie (International ed. in English)·2026

Related Experiment Video

Updated: Jun 17, 2026

Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film
08:23

Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film

Published on: July 10, 2016

Polyanionic Antimicrobial Membranes: An Experimental and Theoretical Study.

Jiangna Guo1, Qiming Xu2, Rongwei Shi3

  • 1Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, Department of Polymer Science and Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University , Suzhou, 215123, China.

Langmuir : the ACS Journal of Surfaces and Colloids
|April 9, 2017
PubMed
Summary
This summary is machine-generated.

New polyanionic membranes demonstrate broad-spectrum antimicrobial activity against bacteria and fungi. These safe, stable materials show potential for healthcare applications, inhibiting biofilm formation and exhibiting good biocompatibility.

More Related Videos

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification
07:32

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification

Published on: April 7, 2017

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions
12:18

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions

Published on: August 3, 2021

Related Experiment Videos

Last Updated: Jun 17, 2026

Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film
08:23

Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film

Published on: July 10, 2016

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification
07:32

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification

Published on: April 7, 2017

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions
12:18

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions

Published on: August 3, 2021

Area of Science:

  • Materials Science
  • Biotechnology
  • Polymer Chemistry

Background:

  • Polycationic polymers are established antimicrobial agents with broad-spectrum activity.
  • There is a need for novel antimicrobial materials with enhanced efficacy and safety profiles for healthcare applications.

Purpose of the Study:

  • To synthesize and characterize novel polyanionic antimicrobial membranes.
  • To evaluate the antimicrobial efficacy, antibiofilm activity, and biocompatibility of these membranes.

Main Methods:

  • In situ photo-cross-linking of a sulfate-based anionic monomer.
  • Cation-exchange with organic (quaternary ammonium, imidazolium) or metal (Ag+, Cu2+, Fe3+, Zn2+, Na+, K+) cations.
  • Antimicrobial activity testing against bacteria (Escherichia coli, Staphylococcus aureus) and fungi (Candida albicans).
  • Biofilm inhibition assays using Candida albicans strains.
  • Assessment of blood compatibility, cytotoxicity, and long-term stability.

Main Results:

  • Synthesized polyanionic membranes exhibited high and broad-spectrum antimicrobial activity.
  • Efficient inhibition of biofilm formation by Candida albicans strains was observed.
  • The membranes demonstrated good blood compatibility, low cytotoxicity, and long-term antibacterial stability.

Conclusions:

  • Polyanionic antimicrobial membranes can be effectively synthesized via photo-cross-linking and cation-exchange.
  • These membranes represent promising, safe antimicrobial materials for healthcare settings.
  • The developed materials offer a viable alternative to traditional antibiotics with potential for biofilm control.