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Cardiovascular Gene Therapy: Past, Present, and Future.
Seppo Ylä-Herttuala1, Andrew H Baker2
1A.I. Virtanen Institute, University of Eastern Finland, Yliopistonranta 1, 70211 Kuopio, Finland; Heart Center and Gene Therapy Unit, Kuopio University Hospital, PO Box 100, 70029 KYS Kuopio, Finland.
Summary
Gene therapy offers a promising approach for cardiovascular diseases, addressing unmet needs in conditions like heart failure and ischemia. Recent advances in gene delivery and vector technology are driving new clinical trials for these complex conditions.
Area of Science:
- Cardiovascular Medicine
- Gene Therapy
- Molecular Biology
Background:
- Cardiovascular diseases (CVDs) represent a significant global health burden.
- Conventional treatments for CVDs have limitations, leaving unmet clinical needs.
- Gene therapy presents a potential therapeutic avenue for acquired and inherited cardiovascular conditions.