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Acquired Brucella bacteraemia in a young infant
Ambar Bhatnagar1, Daisy Khera2, Kuldeep Singh1
1Department of Peadiatrics, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
BMJ Case Reports
|April 9, 2017
Summary
Brucellosis can cause failure to thrive in infants. Early diagnosis and treatment with antibiotics like amikacin and rifampicin lead to satisfactory weight gain and recovery.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Brucellosis is a zoonotic infection that can affect humans.
- Infants are susceptible to acquiring infections through contaminated food sources.
- Failure to thrive (FTT) is a common pediatric concern requiring thorough etiological investigation.
Observation:
- A 6-week-old infant presented with persistent failure to thrive, fever, and lethargy.
- The infant was exclusively fed unpasteurized diluted goat's milk since birth.
- Brucellosis was confirmed via blood culture and serological testing.
Findings:
- The infant was diagnosed with acquired brucellosis.
- Maternal serology for Brucella was negative, suggesting infant-acquired infection.
- Treatment with amikacin and rifampicin resulted in successful recovery and weight gain.
Implications:
- Acquired brucellosis is a critical differential diagnosis for failure to thrive in young infants.
- This case highlights the importance of considering environmental and dietary exposures in infant infections.
- Prompt diagnosis and appropriate antibiotic therapy are crucial for favorable outcomes in pediatric brucellosis.