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Translational synthetic biology.

Mamta Singh1, Anuradha Vaidya1

  • 1Symbiosis School of Biomedical Sciences (SSBS), Symbiosis International University (SIU), Symbiosis Knowledge Village, Lavale, Mulshi, Pune, 412115 India.

Systems and Synthetic Biology
|April 11, 2017
PubMed
Summary
This summary is machine-generated.

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Synthetic biology enables engineering biological systems for applications, including novel drug development. Current methods offer probabilistic, not precise, control, but advancements are accelerating therapeutic innovation.

Area of Science:

  • Synthetic biology
  • Biological engineering
  • Computational biology

Background:

  • Synthetic biology aims to engineer biological systems using computational design principles.
  • Current synthetic biology approaches offer probabilistic control, not precise engineering.
  • The field is increasingly applied to human health and novel drug development.

Discussion:

  • Recent advancements in synthetic biology show promise for developing novel human health applications.
  • The review focuses on translational developments and emerging trends in synthetic biology for drug discovery.
  • The integration of computational tools is key to enhancing the precision of biological engineering.

Key Insights:

  • Synthetic biology enables the engineering of biological systems using existing and novel components.
Keywords:
CancerMalariaNeurodegenerativeSynthetic biologyTranslationalTuberculosis

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  • The development of new drugs is a key application area for synthetic biology.
  • Despite current limitations, the field is progressing towards more precise biological engineering.

    • Outlook:

    • Future developments are expected to enhance the precision and applicability of synthetic biology.
    • Continued research will likely lead to more sophisticated drug discovery and development pipelines.
    • Synthetic biology holds significant potential for addressing unmet needs in human health.