Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Restricted Blood Flow Exercise in Sedentary, Overweight African-American Females May Increase Muscle Strength and

Vernon Bond1, Bryan Heath Curry2, Krishna Kumar3

  • 1Department of Recreation, Human Performance & Leisure Studies and Exercise Science & Human Nutrition Laboratory, Howard University Cancer Centre, Washington DC, United States of America.

Journal of Pharmacopuncture
|April 11, 2017
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From knowledge graph to topological data analysis: a novel framework to analyze gene regulatory networks for tomato-multi-pathogen interactions.

The New phytologist·2026
Same author

Emotional intelligence: An important skill to learn now more than ever.

F1000Research·2026
Same author

A Global Survey on Intra-operative Neuromonitoring (IONM) Practices, Attitudes Towards Its Use, and Barriers Among Spine Surgeons.

Global spine journal·2026
Same author

The therapeutic potential of N-acetylcysteine across multiple organ systems: a narrative review.

La Clinica terapeutica·2026
Same author

Amping Up Receptor Balance and Bias: Fine Tuning of Unimolecular Multiagonists.

Journal of medicinal chemistry·2026
Same author

Optimizing breast cancer treatment strategies through fractional-order dynamics: A computational modeling approach.

PloS one·2026

Low-load resistance training with restricted blood flow significantly boosts muscle strength. However, this exercise method may impair vascular autoregulation and endothelial function, warranting further investigation.

Area of Science:

  • Exercise Physiology
  • Vascular Biology
  • Sports Medicine

Background:

  • Low-load resistance training with restricted blood flow is a potential strength-building method for individuals unable to perform high-load training.
  • This exercise modality has shown variable effects on blood vessel function, potentially contributing to dysfunction.

Purpose of the Study:

  • To test if unilateral resistance training of leg extensors with partially restricted blood flow enhances muscle strength.
  • To determine the impact of this training on vascular autoregulation.

Main Methods:

  • Nine overweight, young adult African-Americans with low cardiorespiratory fitness underwent unilateral quadriceps femoris muscle training.
  • Training involved partially restricted blood flow at 30% of 1-repetition maximum (1-RM) for 3 weeks.
Keywords:
quadriceps femorisresistance trainingskeletal muscleKaatsu

Related Experiment Videos

  • Muscle strength (1-RM) and post-occlusion blood flow (reactive hyperemia) were measured.
  • Main Results:

    • A significant increase in 1-RM load was observed in the trained legs (77 ± 3 to 84 ± 4 kg, P < 0.05).
    • No significant change in 1-RM load occurred in the untrained legs (P > 0.1).
    • Post-occlusion blood flow significantly decreased in trained legs (19 ± 2 to 13 ± 2 mL·min⁻¹·dL⁻¹, P < 0.05) and marginally in untrained legs (18 ± 2 to 16 ± 1 mL·min⁻¹·dL⁻¹, P = 0.09).

    Conclusions:

    • Restricted blood flow exercise effectively increases muscle strength.
    • This training approach may lead to decrements in endothelial function and vascular autoregulation.
    • Further research is needed to explore potential treatments for exercise-induced vascular dysfunction.