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1-D blood flow modelling in a running human body
1a Department of Hydrodynamic Systems , Budapest University of Technology and Economics , Budapest , Hungary.
Computer Methods in Biomechanics and Biomedical Engineering
|April 11, 2017
Summary
Simulating blood flow in running humans shows motion significantly alters blood pressure and flow rate amplitudes. Average values remain largely unaffected by movement, highlighting dynamic physiological responses.
Area of Science:
- Biomechanics
- Cardiovascular Physiology
- Computational Fluid Dynamics
Background:
- Understanding blood flow dynamics is crucial for cardiovascular health.
- Previous models often simplified arterial networks by assuming immobility.
- Incorporating motion effects is essential for realistic physiological simulations.
Purpose of the Study:
- To simulate blood flow in a mobile human arterial network during running.
- To modify an existing immobile one-dimensional (1-D) model to account for motion.
- To investigate the impact of running speed on blood flow parameters.
Main Methods:
- Modified a previously published immobile 1-D arterial network model.
- Included an inertial force term in the momentum equation to simulate motion.
- Utilized gait analysis data at various speeds to calculate inertial forces.
Main Results:
- Observed significant changes in the amplitudes of blood pressure and flow rate due to motion.
- Found that average blood pressure and flow rate values were not significantly affected by motion.
- Demonstrated the influence of dynamic movement on pulsatile hemodynamic parameters.
Conclusions:
- Running motion significantly impacts the dynamic characteristics of blood flow.
- The modified 1-D model provides a more realistic simulation of blood flow in mobile subjects.
- Further research can explore the clinical implications of motion-induced hemodynamic variations.