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Clinical features and current management of chronic granulomatous disease
C B Forrest1, J R Forehand, R A Axtell
1Children's Hospital of Pennsylvania, Philadelphia.
Hematology/Oncology Clinics of North America
|June 1, 1988
Abstract:
Chronic granulomatous disease (CGD) is a diverse disorder characterized by several clinical presentations and a multitude of metabolic defects. The authors summarize the clinical features and current management of CGD, offer a definition of the disease based on molecular defects of the respiratory burst, and present their experience with trimethoprim/sulfamethoxazole prophylaxis.