Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Structure-Function Relationship Between the Bruch Membrane Opening-based Minimum Rim Width and Visual Field Defects

Serhat Imamoglu1, Nimet Burcu Celik, Mehmet S Sevim

  • 1*Haydarpasa Numune Training and Research Hospital, Istanbul †University of Pamukkale Medical Faculty, Denizli, Turkey.

Journal of Glaucoma
|April 11, 2017
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beyond the Cornea: Early Changes in Scleral, Iris, and Corneal Parameters After Corneal Collagen Cross-Linking.

Journal of clinical medicine·2026
Same author

Arterial stiffness and choroidal vascularity index in autosomal dominant polycystic kidney disease with preserved kidney function.

Clinical nephrology·2026
Same author

Surgical Outcomes of Ahmed Glaucoma Valve in Neovascular Glaucoma Secondary to Diabetic Retinopathy Versus Central Retinal Vein Occlusion.

Journal of glaucoma·2025
Same author

Outcomes of gonioscopy-assisted 360-degree suture trabeculotomy in pseudoexfoliation glaucoma.

International ophthalmology·2025
Same author

Does completion time of the initiation phase of anti-vascular growth factor affect visual and anatomical outcomes?: The MARMASIA study group report No.5.

Eye (London, England)·2025
Same author

Effects of uncomplicated phacoemulsification surgery on retinal vascular diameters, subfoveal choroidal and central macular thickness.

International ophthalmology·2025

Localized Bruch

Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Medical Imaging

Background:

  • Glaucoma is a leading cause of irreversible blindness.
  • Accurate assessment of visual field sensitivity is crucial for glaucoma management.
  • Spectral-domain optical coherence tomography (SD-OCT) offers detailed structural imaging of the optic nerve head.

Purpose of the Study:

  • To investigate the relationship between Bruch's membrane opening-minimum rim width (BMO-MRW) parameters and visual field (VF) sensitivity in advanced glaucoma.
  • To evaluate the correlation of global and temporal BMO-MRW with visual field parameters using SD-OCT and the 10-2 visual field test.

Main Methods:

  • A cross-sectional study of 33 eyes from 29 patients with advanced glaucoma.
  • Automated white-on-white perimetry (Humphrey field analyzer) was used to assess VF sensitivity (Mean Deviation and Pattern Standard Deviation).

Related Experiment Videos

  • SD-OCT was employed to measure BMO-MRW and peripapillary retinal nerve fiber layer thickness, with specific focus on the 90-degree temporal sector.

    • Main Results:

    • Upper and lower temporal BMO-MRW parameters demonstrated stronger correlations with corresponding visual field Mean Deviation values compared to global and temporal MRW.
    • Global and temporal retinal nerve fiber layer thickness also correlated with global Mean Deviation.

    Conclusions:

    • High correlation found between localized BMO-MRW measurements (upper/lower temporal sectors) and 10-2 visual field sensitivity.
    • Localized BMO-MRW may predict visual hemifield status in patients unable to complete VF testing.
    • Further longitudinal studies are recommended to assess BMO-MRW for monitoring glaucoma progression.