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Updated: Jan 31, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
Persistent intestinal bleeding due to severe CMV-related thrombocytopenia in a preterm newborn
Alberto Berardi1, Eugenio Spaggiari1, Chiara Cattelani1
1a Dipartimento Integrato Materno-Infantile , Terapia Intensiva Neonatale, Azienda Ospedaliero-Universitaria Policlinico , Modena , Italy.
Abstract:
The optimal threshold for neonatal platelet transfusions in sick newborns is still uncertain. We report a congenital cytomegalovirus (CMV) infection in a premature neonate with severe thrombocytopenia who subsequently presented with necrotizing enterocolitis and intestinal bleeding. The baby recovered after platelet transfusions were discontinued and the therapy was switched from intravenous ganciclovir to oral valganciclovir. We discuss both measures, speculating on the key role of platelet transfusions.
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