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Derivation of human iPS cell lines from monozygotic twins in defined and xeno free conditions

Elias Uhlin1, Harriet Rönnholm1, Kelly Day1

  • 1Karolinska Institutet, Department of Neuroscience, Retziusvag 8, 171 77 Stockholm, Sweden.

Stem Cell Research
|April 12, 2017
PubMed

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Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...