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Related Experiment Videos

Cerebral aneurysm blood flow simulations are sensitive to basic solver settings.

Kendall D Dennis1, David F Kallmes2, Dan Dragomir-Daescu3

  • 1Division of Engineering, Mayo Clinic, Rochester, MN, USA.

Journal of Biomechanics
|April 12, 2017
PubMed
Summary
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Computational fluid dynamics (CFD) simulations for cerebral aneurysms require careful selection of timestep and residual error values. Optimizing these parameters ensures accuracy and computational efficiency, preventing compounding errors in hemodynamic analysis.

Area of Science:

  • Biomedical Engineering
  • Computational Fluid Dynamics (CFD)
  • Medical Imaging and Simulation

Background:

  • Computational modeling of peri-aneurysmal hemodynamics is crucial for understanding aneurysm behavior.
  • Commercial software often lacks transparency regarding input value sensitivity.
  • Previous studies have not fully explored the impact of timestep and residual errors on hemodynamic outputs.

Purpose of the Study:

  • To perform a formal sensitivity analysis and optimization of computational fluid dynamics (CFD) solver settings for cerebral aneurysm models.
  • To investigate the impact of varying timestep duration and model residual error on hemodynamic outputs.
  • To optimize solver settings for computational efficiency while maintaining solution accuracy.

Main Methods:

Keywords:
AneurysmCFDHemodynamicsSensitivity

Related Experiment Videos

  • Three cerebral aneurysm models were simulated using ANSYS Fluent.
  • Sensitivity analysis was conducted on timestep sizes (10-3s, 10-4s, 10-5s) and residual error values (10-4, 10-5, 10-6).
  • Simulations were compared quantitatively and qualitatively against a baseline of 10-5s timestep and 10-6 residual error.

    • Main Results:

    • A timestep of 10-4s and residual error of 10-5 provided converged solutions with <1% RMS error in mean velocity and wall shear stress (WSS) for all models.
    • This optimized setting reduced simulation time by over 85% for complex flow models compared to the baseline.
    • The least accurate settings (10-3s timestep, 10-4 residual error) still predicted the dominant vortex but showed up to 20% RMS error in velocity and WSS.

    Conclusions:

    • Sufficiently small timestep size and residual error are essential for accurate time-dependent flow characteristics in cerebral aneurysm CFD simulations.
    • Inadequate resolution in both timestep and residual error can lead to compounding errors, compromising results.
    • Optimized solver settings balance computational efficiency and solution accuracy for reliable hemodynamic analysis.