Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diffraction data of core-shell nanoparticles from an X-ray free electron laser.

Xuanxuan Li1,2, Chun-Ya Chiu3, Hsiang-Ju Wang3

  • 1Complex Systems Division, Beijing Computational Science Research Center, ZPark II, Haidian, Beijing 100193, China.

Scientific Data
|April 12, 2017
PubMed

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantifying optical scattering losses in pump-probe serial femtosecond crystallography experiments.

IUCrJ·2026
Same author

Coronavirus membrane protein with a fluorescent protein tag enables particle tracking for the study of virus assembly and egress in live cells.

Journal of virology·2026
Same author

Access to general practice: why policy must be rural-proofed.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same author

High-throughput in situ single particle X-ray imaging of dehydrating viral capsids.

Light, science & applications·2026
Same author

A Thermosensitive Hydrogel Embedded with Metronidazole-Derived Carbon Dots for Antibacterial Treatment of Periodontitis.

International journal of nanomedicine·2026
Same author

Single-Particle X-ray Scattering Reveals a High Local Supersaturation of Precursors as the Origin of CoO Assembly Formation.

The journal of physical chemistry letters·2026
Summary

Single particle analysis using X-ray free-electron lasers successfully characterized nanoscale core-shell nanoparticles. This research provides valuable data for developing advanced algorithms in single particle scattering.

Area of Science:

  • Materials Science
  • Nanotechnology
  • X-ray Physics

Background:

  • X-ray free-electron lasers (XFELs) offer advanced capabilities for nanoscale particle analysis.
  • Coherent diffractive imaging (CDI) is a powerful technique for probing single particles.
  • Understanding the structure of core-shell nanoparticles is crucial for various applications.

Purpose of the Study:

  • To perform single particle analysis on inorganic core-shell nanoparticles using XFELs.
  • To evaluate the potential of CDI for determining nanoparticle size distribution.
  • To create a dataset of scattering patterns for algorithm development.

Main Methods:

  • Coherent diffractive imaging experiments were conducted at the Linac Coherent Light Source (LCLS).
  • Single inorganic gold core-palladium shell nanoparticles were exposed to femtosecond hard-X-ray pulses.

Related Experiment Videos

  • Scattered intensities were recorded and analyzed to determine nanoparticle characteristics.

    • Main Results:

    • Scattering patterns were obtained with a resolution of approximately 7 nm.
    • Analysis of scattering data revealed the size distribution of the nanoparticles.
    • The determined size distribution was consistent with electron microscopy results.
    • A valuable dataset of single particle scattering patterns was compiled.

    Conclusions:

    • XFEL-based CDI is effective for single particle analysis of core-shell nanoparticles.
    • The compiled dataset can significantly aid the development of single particle scattering algorithms.
    • This study demonstrates the utility of XFELs for nanoscale materials characterization.