Related Experiment Videos
Serotonergic and noradrenergic sensitivity in obsessive-compulsive disorder: behavioral findings
1Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032.
The American Journal of Psychiatry
|August 1, 1988
Abstract:
Six of eight patients with obsessive-compulsive disorder had an exacerbation of symptoms when given m-chlorophenylpiperazine. Fenfluramine and placebo produced mild improvement. Six patients given intravenous clonidine experienced marked reduction in obsessions. Implications for serotonergic and noradrenergic hypotheses of obsessive-compulsive disorder are discussed.