Validity of electrocardiographic criteria for increased left ventricular mass in young patients in the general population
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Updated: Jun 12, 2026
Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery
Published on: February 20, 2017
Eduard Sklyar1, Paul Ginelli1, Aaron Barton1
1Eduard Sklyar, Paul Ginelli, Aaron Barton, Richard Peralta, Jonathan N Bella, Department of Medicine, Bronx-Lebanon Hospital Center, Bronx, NY 10457, United States.
Aim:
To investigate validity of electrocardiographic (ECG) criteria for left ventricular hypertrophy (LVH) in young adults.
Methods:
Retrospectively, echocardiograms showing LVH and concomitant electrocardiograms were collected in patients 18 to 39 years old. A control group of patients without LVH was collected. Using echocardiogram as the gold standard, electrocardiograms were analyzed using common voltage criteria.
Results:
Study included 100 subjects (52% male, mean age = 28 ± 6.8 years, 96% Hispanic or African-American) with 50% LVH prevalence. Sensitivity and specificity for Sokolow-Lyon criteria were 24% (95%CI: 13.5%-38.4%) and 88% (95%CI: 74.9%-95%). For Cornell criteria, sensitivity was 32% (95%CI: 19.9%-46.8%) and specificity 98% (95%CI: 87.9%-99.8%). For R in aVL criteria, sensitivity was 12% (95%CI: 4.9%-25%) and specificity 100% (95%CI: 91.1%-100%).
Conclusion:
In young adults common ECG voltage criteria have low sensitivities and high specificities similar to other age groups. Low sensitivities preclude these ECG criteria from serving as effective screening tests.
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