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Related Experiment Videos

Hepatitis A to E: what's new?

Waled Mohsen1, Miriam T Levy1,2

  • 1Department of Gastroenterology and Hepatology, Liverpool Hospital, Sydney, New South Wales, Australia.

Internal Medicine Journal
|April 13, 2017
PubMed
Summary

Viral hepatitis (hepatitis A to E) causes significant global health issues. This review covers current evidence for screening, diagnosis, and treatment, highlighting new hepatitis C therapies and hepatitis B management strategies.

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Area of Science:

  • Hepatology
  • Infectious Diseases
  • Public Health

Background:

  • Viral hepatitis (hepatitis A-E) is a major cause of global morbidity and mortality.
  • Chronic infections and underutilization of therapies increase rates of cirrhosis and hepatocellular carcinoma.
  • A comprehensive review of current evidence is needed for effective management.

Purpose of the Study:

  • To review current evidence for screening, diagnosis, and treatment of viral hepatitis A to E.
  • To highlight recent advancements in viral hepatitis therapies, particularly for hepatitis C.
  • To provide practical guidance for managing hepatitis B, including in specific populations.

Main Methods:

  • Systematic review of international and Australian guidelines.
  • Inclusion of high-quality clinical trials.
Keywords:
hepatitis Ahepatitis Bhepatitis Chepatitis Dhepatitis Etreatment

Related Experiment Videos

  • MEDLINE database search using structured keywords.

    • Main Results:

    • Direct-acting antiviral therapies for hepatitis C are safe, effective, well-tolerated, and accessible in Australia.
    • Evidence for the efficacy and safety of hepatitis B treatment is outlined, with considerations for pregnancy and immunosuppression.
    • A simplified model for understanding the five phases of hepatitis B is presented.

    Conclusions:

    • Current evidence supports effective screening, diagnosis, and treatment strategies for viral hepatitis A-E.
    • New direct-acting antivirals have transformed hepatitis C management.
    • Evidence-based guidelines are crucial for optimal patient outcomes in viral hepatitis care.