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Cobalt-catalysed Markovnikov selective hydroboration of vinylarenes
Jingying Peng1, Jamie H Docherty1, Andrew P Dominey2
1EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, UK. stephen.thomas@ed.ac.uk.
Chemical Communications (Cambridge, England)
|April 13, 2017
Abstract:
A bipyridiyl-oxazoline cobalt catalyst BPOCoCl2 has been developed for the Markovnikov selective hydroboration of alkenes using pinacolborane and NaOtBu as the in situ activator with up to >98 : 2 branched : linear selectivity (24 examples, 45-92% isolated yield).