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Olfactory Bulb Volume Changes in Patients With Nasal Septal Deviation.
Mahmut Özkiriş1, Zeliha Kapusuz Gencer, Reha Aydin
1*Department of Otolaryngology, Head and Neck Surgery, Bozok University Medical Faculty†Neurology Department of Yozgat State Hospital‡Department of Psychiatry, Bozok University Medical Faculty, Yozgat, Turkey.
The Journal of Craniofacial Surgery
|April 14, 2017
Summary
Severe nasal septal deviations significantly impact olfactory bulb (OB) volumes, with contralateral OBs being larger. Mild to moderate deviations showed no significant effect on OB size.
Area of Science:
- Neuroscience
- Otolaryngology
- Radiology
Background:
- The olfactory bulb (OB) is crucial for processing olfactory information.
- Nasal septal deviation can potentially influence sinonasal structures and functions.
Purpose of the Study:
- To investigate olfactory bulb volume changes in patients with nasal septal deviation.
- To explore the association between the severity of nasal septal deviation and OB volume.
Main Methods:
- A cross-sectional study involving 90 patients with isolated nasal septal deviations.
- Cranial MRI (T2-weighted coronal images) was used to evaluate olfactory bulb volumes via planimetric manual contouring.
Main Results:
- Severe nasal septal deviations (≥15°) were associated with statistically significant increases in olfactory bulb volumes.
- Contralateral olfactory bulb volumes were significantly larger than ipsilateral volumes in the severe deviation group.
- Mild (<9°) and moderate (9°-15°) septal deviations did not show significant effects on olfactory bulb volumes.
Conclusions:
- Severe nasal septal deviations significantly impact olfactory bulb volumes.
- The contralateral olfactory bulb may enlarge in cases of severe septal deviation.
- Further research is needed to determine the clinical significance of these OB volume changes.