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Related Experiment Videos

Fiber to the rescue?

Vasiliki Michopoulos1

  • 1Department of Psychiatry & Behavioral Sciences, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA.

Science Translational Medicine
|April 14, 2017
PubMed
Summary
This summary is machine-generated.

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Dietary fiber intake can mitigate the negative inflammatory responses triggered by consuming high-fat, high-calorie meals. This finding highlights fiber

Area of Science:

  • Nutrition science
  • Immunology
  • Gastroenterology

Background:

  • High-fat, high-calorie meals can induce systemic inflammation.
  • Inflammation is linked to various chronic diseases.
  • Dietary fiber's role in modulating inflammatory responses is an area of active research.

Purpose of the Study:

  • To investigate the impact of fiber supplementation on the proinflammatory effects of consuming a high-fat, high-calorie meal.

Main Methods:

  • Participants consumed a standardized high-fat, high-calorie meal.
  • Fiber supplementation was administered to a subset of participants.
  • Proinflammatory markers were measured before and after meal consumption.

Main Results:

Related Experiment Videos

  • Fiber supplementation significantly reduced the increase in key proinflammatory markers post-meal.
  • Unsupplemented participants showed a marked elevation in inflammatory markers.

Conclusions:

  • Fiber supplementation effectively counteracts the acute proinflammatory effects of high-fat, high-calorie meals.
  • This suggests a potential dietary strategy for managing meal-induced inflammation.