Editorial: Hybrid Compounds as Multitarget Agents in Medicinal Chemistry - Part I

From Xenobiotic Exposure to Neuroinflammation: Mechanisms Linking Lipopolysaccharide Signaling to Depressive-like Behavior.

Journal of xenobiotics·2026

Neuroinflammation in Epilepsy: Biochemical and Molecular Mechanisms and Implications for Natural Product-Driven Drug Discovery.

International journal of molecular sciences·2026

Anti-inflammatory potential of the CISACN adduct in LPS-induced murine models.

Inflammopharmacology·2026

Ribifolones A-H, New Macrocyclic Diterpenes from Jatropha ribifolia, Their Cytotoxic Activity and Insights Supported by Network Pharmacology and Molecular Modeling.

Molecules (Basel, Switzerland)·2026

A Review of Pathophysiology and Computational Studies of Isoeugenol Derived Acetamides against Alzheimer's Disease.

Current topics in medicinal chemistry·2026

Antinociceptive Effect of Cinnamaldehyde in Male Mice: Investigation of the Mechanisms of Action Through In Silico and In Vivo Approaches.

Chemistry & biodiversity·2026

Targeting Autoimmunity in Type 1 Diabetes: Emerging Immunomodulatory Therapies.

Current topics in medicinal chemistry·2026

Epigenetic Modifiers and Synthetic Lethality in Cancer Therapy: Emerging Targets Beyond Traditional Approaches.

Current topics in medicinal chemistry·2026

Total Flavonoids from Hawthorn Leaves Alleviate Acute Inflammatory Responses Following Spinal Cord Injury by Downregulating the TLR4/NF-Κb Signaling Pathway.

Current topics in medicinal chemistry·2026

Ferulic Acid and Brain Health: A Defender Against Alzheimer's Disease, Parkinson's Disease, and Neuroinflammation.

Current topics in medicinal chemistry·2026

1-Deazapurine-Based Alpha-Glucosidase Inhibitors: A Computational Approach for the Treatment of Type 2 Diabetes Mellitus.

Current topics in medicinal chemistry·2026

Systematic Review of Hybrid Nanosystems as Emerging Tools in Targeted Cancer Therapy and Future Aspects.

Current topics in medicinal chemistry·2026

Experimental and In Silico Evaluation of Honey-Derived Phenolic Compounds: Antioxidant Activity, Anti-Inflammatory Potential Pharmacokinetic Properties, Toxicity Assessment, and Multitarget Anti-Inflammatory Potential.

Oxidative medicine and cellular longevity·2026

Chemical constituents in safflower leaves and inhibitory effects of quercetin and luteolin derivatives on osteoclast differentiation.

Pharmaceutical biology·2026

Metal Oxides Catalyze Formation of Dehydroamino Acids by Phosphate β-Elimination Under Physiological Conditions.

Angewandte Chemie (International ed. in English)·2026

LC-MS- and Bioactivity-Guided Discovery of Novel Cyclohexenyl Chalcones from the Edible Rhizomes of Boesenbergia rotunda and Evaluation of Their Anticancer Activities against Colorectal Cancer.

Journal of agricultural and food chemistry·2026

Bioactive Terpenoids and Steroids from Astragalus complanatus Seeds underlie Its Potent Neuroprotective Efficacy In Vitro and In Vivo.

Journal of agricultural and food chemistry·2026

Novel N-Phenylphthalimide Derivatives as Protoporphyrinogen IX Oxidase-Targeted Inhibitor Herbicides.

Journal of agricultural and food chemistry·2026

Related Experiment Videos

Editorial: Hybrid Compounds as Multitarget Agents in Medicinal Chemistry - Part I

Related Concept Videos

From Xenobiotic Exposure to Neuroinflammation: Mechanisms Linking Lipopolysaccharide Signaling to Depressive-like Behavior.

Neuroinflammation in Epilepsy: Biochemical and Molecular Mechanisms and Implications for Natural Product-Driven Drug Discovery.

Anti-inflammatory potential of the CISACN adduct in LPS-induced murine models.

Ribifolones A-H, New Macrocyclic Diterpenes from Jatropha ribifolia, Their Cytotoxic Activity and Insights Supported by Network Pharmacology and Molecular Modeling.

A Review of Pathophysiology and Computational Studies of Isoeugenol Derived Acetamides against Alzheimer's Disease.

Antinociceptive Effect of Cinnamaldehyde in Male Mice: Investigation of the Mechanisms of Action Through In Silico and In Vivo Approaches.

Targeting Autoimmunity in Type 1 Diabetes: Emerging Immunomodulatory Therapies.

Epigenetic Modifiers and Synthetic Lethality in Cancer Therapy: Emerging Targets Beyond Traditional Approaches.

Total Flavonoids from Hawthorn Leaves Alleviate Acute Inflammatory Responses Following Spinal Cord Injury by Downregulating the TLR4/NF-Κb Signaling Pathway.

Ferulic Acid and Brain Health: A Defender Against Alzheimer's Disease, Parkinson's Disease, and Neuroinflammation.

1-Deazapurine-Based Alpha-Glucosidase Inhibitors: A Computational Approach for the Treatment of Type 2 Diabetes Mellitus.

Systematic Review of Hybrid Nanosystems as Emerging Tools in Targeted Cancer Therapy and Future Aspects.

Experimental and In Silico Evaluation of Honey-Derived Phenolic Compounds: Antioxidant Activity, Anti-Inflammatory Potential Pharmacokinetic Properties, Toxicity Assessment, and Multitarget Anti-Inflammatory Potential.

Chemical constituents in safflower leaves and inhibitory effects of quercetin and luteolin derivatives on osteoclast differentiation.

Metal Oxides Catalyze Formation of Dehydroamino Acids by Phosphate β-Elimination Under Physiological Conditions.

LC-MS- and Bioactivity-Guided Discovery of Novel Cyclohexenyl Chalcones from the Edible Rhizomes of Boesenbergia rotunda and Evaluation of Their Anticancer Activities against Colorectal Cancer.

Bioactive Terpenoids and Steroids from Astragalus complanatus Seeds underlie Its Potent Neuroprotective Efficacy In Vitro and In Vivo.

Novel N-Phenylphthalimide Derivatives as Protoporphyrinogen IX Oxidase-Targeted Inhibitor Herbicides.

Related Experiment Videos

Editorial: Hybrid Compounds as Multitarget Agents in Medicinal Chemistry - Part I

Related Concept Videos

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