Scintigraphic imaging of technetium 99m-labeled neutrophils in the dog

Autologous canine neutrophils were labeled with technetium 99m and reinjected in 7 dogs with experimentally induced focal abscesses to determine the ability of scintigraphy to localize a focus of sepsis (abscess). Good localization of labeled cells in an abscess was achieved; however, a large portion of the technetium 99m eluted from the neutrophils.