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Related Experiment Videos

Histology of human cementum: Its structure, function, and development.

Tsuneyuki Yamamoto1, Tomoka Hasegawa1, Tomomaya Yamamoto1

  • 1Department of Developmental Biology of Hard Tissue, Hokkaido University Graduate School of Dental Medicine, Kita 13, Nishi 7, Kita-ku, Sapporo 060-8586, Japan.

The Japanese Dental Science Review
|April 15, 2017
PubMed
Summary

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This review clarifies human cementum histology, structure, function, and development. It corrects misconceptions arising from comparisons with rodent cementum in dental science research.

Area of Science:

  • Dental Sciences
  • Histology
  • Biomineralization

Background:

  • Cementum biology has been studied for ~180 years using advanced microscopy.
  • Extensive data on cementum histology exist from human and animal studies, particularly rodents.
  • Previous human cementum histology reviews contain questionable conclusions, often due to rodent comparisons.

Purpose of the Study:

  • To present current understanding of human cementum histology, including its structure, function, and development.
  • To critically re-evaluate controversial and questionable conclusions from prior cementum research.
  • To differentiate human cementum characteristics from those of rodent models.

Main Methods:

  • Literature review of historical and current research on cementum histology.
Keywords:
Acellular extrinsic fiber cementumCellular intrinsic fiber cementumCellular mixed stratified cementumExtrinsic fibersHuman cementumIntrinsic fibers

Related Experiment Videos

  • Comparative analysis of human and rodent cementum characteristics.
  • Histological examination and advanced imaging techniques (implied).

    • Main Results:

    • Established detailed current histological features of human cementum.
    • Identified and addressed specific areas of controversy in human cementum literature.
    • Highlighted key differences between human and rodent cementum, clarifying previous misinterpretations.

    Conclusions:

    • Accurate understanding of human cementum histology is crucial for dental sciences.
    • Previous comparative studies with rodents have led to significant misunderstandings.
    • This review provides a foundation for future research on human cementum biology and pathology.